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SAYPHA® FILLER with Lidocaine

Manufacturer: Croma
Active Substance(s) : Sodium hyaluronate, lidocaine
Strength: 23mg/ml, 3mg/ml
Pack Size: 1-1ml prefilled syringe
Accessories: Package insert, 2-27G 1/2” needles, 2 traceability labels
Other Known Names: PRINCESS® FILLER with Lidocaine
You can save $18.00 if you add an additional 5 units to your cart.

Saypha Filler with Lidocaine is a soft tissue injectable that fills wrinkles and lines and augments lips to correct the visible signs of aging. When injected into the skin, the cross-linked hyaluronic acid fills skin, an action that leads to the smoothing out of skin depressions and lifting of facial areas. This hyaluronic acid-based dermal injectable instantly works to provide the client with natural, long-lasting results. This aesthetic filler is formulated with a local anesthetic for pain management.

What is Saypha Filler with Lidocaine formulated to do?

Saypha Filler with Lidocaine is primarily made of reticulated hyaluronic acid, a modified form of naturally occurring hyaluronic acid that is present in abundance in the extracellular matrix of dermal tissue. Saypha products are manufactured using an innovative technology called Supreme Monophasic and Reticular Technology, or S.M.A.R.T., that increases filler longevity by optimizing the cross-linking process as well as the viscoelastic properties of the gel. This gel is implanted into the mid to deep dermis via intradermal injection for the purposes of treating moderate to severe facial wrinkles and folds, and to add volume to the lips. This dermal filler is supplemented with lidocaine for pain relief during treatment. As the hyaluronic acid in Saypha Filler with Lidocaine is not derived from animal sources, there is little risk of an allergic reaction occurring. This filler is suitable to be used on all skin types.


Saypha Filler with Lidocaine is a product of Croma-Pharma GmbH, a leading specialist in the development of hyaluronic acid-based technologies and solutions in the fields of orthopedics, aesthetics, and ophthalmology.

Saypha Filler with Lidocaine is made in Austria.

Possible Side Effects

As with all injectables, some patients may experience mild side effects, including temporary redness, tenderness, swelling, or bruising at the injected area. These effects are usually mild and should resolve on their own within a week.

There are patients presenting certain conditions that will exclude them from being eligible for treatment. These include patients who tend to develop hypertrophic scarring, who have a history of auto–immune disease, or who are receiving immune therapy. As well, patients who are known to be hypersensitive to hyaluronic acid, women who are pregnant or breastfeeding, patients under 18 years, or patients who have active skin diseases, inflammation, or infection in the area to be treated should not be treated with this injectable.

Suggested usage

  • This skin filler is meant for injection into the mid to deep dermis.
  • Treatment should be administered by an appropriately trained, licensed medical practitioner.
  • Saypha Filler with Lidocaine may only be injected into non-inflamed, healthy, disinfected skin.
  • Inject this dermal filler using a 27G needle (supplied) with the appropriate injection technique.
  • After the injection, massage the treated area lightly to distribute the product uniformly.
  • Patients should be instructed to minimize physical contact with the treated area (e.g., rubbing or massaging the area) for a few days following treatment to avoid product migration.


This sterile, biodegradable, viscoelastic, clear, transparent, isotonic, homogenized and monophasic gel implant contains reticulated hyaluronic acid at a concentration of 23mg/ml, and lidocaine hydrochloride (0.3%). Other ingredients include phosphate buffer and sodium chloride.

Frequently Asked Questions

What is in the box?

  • 1-1ml prefilled syringe
  • 2-27G½” disposable sterile needles
  • Product leaflet
  • 2 traceability labels

How long do the effects last?

Your patients can enjoy the effects of a Saypha Filler with Lidocaine treatment for up to 6–9 months.

How should it be stored?

This injectable dermal filler should be stored at a temperature range of 2–25°C in a cool, dry place. Protect from light, heat and frost.

When does it expire?

  • The expiry date of the product can be found on the product packaging.
  • Before use, ensure that the product has not passed its expiry date.

Which skin type is it good for?

This treatment is suitable for all skin types; however, it will especially benefit patients who are exhibiting moderate signs of aging such as wrinkles and folds.