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Manufacturer: Merz Pharma
Active Substance(s) : Calcium hydroxylapatite
Pack Size: 1-0.8ml prefilled syringe
Accessories: Package insert

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What is Radiesse® 0.8ml?

Radiesse 0.8ml is a dermal filler gel consisting of calcium hydroxylapatite particles that, when implanted into skin, has the dual action of correcting deep wrinkles and folds like nasolabial folds, while encouraging the skin to produce collagen. By encouraging the natural production of collagen, it helps to extend the results for a longer period of time. Radiesse 0.8ml is indicated for moderate wrinkles. For patients looking to correct deep skin depressions, you can offer Radiesse 1.5ml.

What Radiesse 0.8ml is formulated to do

Over time, the skin of the face tends to lose its youthful appearance, with the onset of wrinkles and facial volume loss. This can be mainly attributed to a loss of dermal tissue caused by thinning of the dermis. Radiesse 0.8ml counteracts these visible signs of facial aging by filling the skin to visibly correct deep cutaneous depressions and restore lost volume to facial features.

Radiesse 0.8ml is made of a biocompatible, non-toxic material called calcium hydroxylapatite. In this skin filler, calcium hydroxylapatite is synthetically manufactured and formed into microspheres that are suspended in a gel carrier. When deposited into the skin through subdermal injection, this skin filler immediately corrects the wrinkle or defect and acts to initiate neocollagenesis at the treatment site. As a result, the implant is gradually replaced by the body’s own natural collagen, further extending the result.


Radiesse 0.8ml is produced by Merz Pharmaceuticals, a global leader in developing and providing therapeutic solutions in the fields of aesthetics and neurotoxins.

Radiesse 0.8ml is manufactured in Europe.

What else you need to know

When can it cause side effects?

While Radiesse treatment is generally regarded as very safe, there can be occasions where use of this product may result in undesired effects. As with all treatments with injectable dermal fillers, the most common reactions experienced with the use of Radiesse are reactions to the injection procedure. This may include bruising, redness, swelling, pain, itching, and other localized side effects.

Certain individuals are not suitable for Radiesse treatments. These include patients with an allergy to any component of the filler; those with a history of multiple and/or severe allergies; those with bleeding disorders; or women who are pregnant or lactating. To avoid adverse reactions, obtain the patients medical history prior to treatment.

Which skin type is it good for?

This dermal filler treatment is suitable for patients with mature, aging skin who are seeking to treat moderate or severe wrinkles and folds, like nasolabial folds and marionette lines.

What it is made without?

Radiesse contains synthetic calcium hydroxylapatite, decreasing the risk of hypersensitivity reactions. This cosmetic injectable does not contain hyaluronic acid.

Information about the packaging

This dermal injection is supplied in a syringe that is packaged in a foil pouch and boxed for convenience.

Is this injectable FDA approved?

Radiesse 0.8ml is a CE marked medical device and is approved by the FDA for numerous aesthetic indications, including injection into the face and backs of the hands.

Differences within the product range

RADIESSE is available in 2 size options, 0.8ml and 1.5ml, allowing for versatility to treat a wide range of conditions. Both sizes are available with and without lidocaine.

Suggested usage

  • Mark the injection sites and disinfect the area(s) with alcohol or a suitable antiseptic.
  • Prepare the syringe by attaching a sterile injection needle to the syringe.
  • Inject the product slowly into the subdermis, using linear threading technique.
  • Massage the treated area gently in order to uniformly distribute the product.

For additional information regarding administration techniques, refer to the product pamphlet.


Radiesse 0.8ml is a sterile, semi-solid, non-pyrogenic, cohesive gel that consists of synthetic calcium hydroxylapatite microspheres of 25–45 µm diameter suspended in a gel carrier. The gel carrier contains sterile water for injection, glycerin and sodium carboxymethylcellulose.

What is in the box?

  • 1-0.8ml prefilled syringe
  • 2-28G needles
  • Packaging insert
  • Traceability labels

Duration of effect

Radiesse 0.8ml offers long-term benefits to the patients, with enduring results that last a year or more.

Storage conditions

Store this dermal injection product at a temperature between 15°C and 32°C. Do not freeze.

Expiry (shelf life)

  • The shelf life of Radiesse 0.8ml is 2 years from the date of manufacture.
  • Do not use the product after its expiration date.