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What is Pluryal® Meso I?

Pluryal Meso I is a mesotherapy injection treatment that is part of the Pluryal Meso line of dermal fillers designed to volumize the skin and reverse the signs of aging. This filler treatment offers deep bio-revitalization that helps to tighten the skin for a more youthful, radiant appearance. The solution is sterile and transparent and contains a mix of hyaluronic acid and an amino acid complex.

What Pluryal Meso I is formulated to do:

Patients can expect Pluryal Meso I to moisturize the skin on a cellular level, which helps to repair damage caused by aging and other external factors including sun damage and pollution. The advanced formula also helps prevent further damage from occurring through an antioxidant complex that fights off harmful free radicals from causing harm. This complex also helps contribute to long lasting results, as it keeps the other active ingredient, hyaluronic acid, from breaking down prematurely. Hyaluronic acid adds hydration that creates plumpness and adds volume, allowing fine lines and wrinkles, including glabella lines, nasolabial folds, and other lines on the cheeks, mouth, and chin, to be smoothed out. This treatment is ideal for younger skin that is just starting to show the signs of aging, and is most effective in treating patients between 20 to 40 years of age.


Pluryal Meso I is manufactured in Europe and distributed by MD Skin Solutions, who specialize in providing safe and long lasting anti-aging solutions.


The hyaluronic acid in this dermal injectable is of non-animal origin and is manufactured in a laboratory.

What else you need to know:

Pluryal Meso I is extremely biocompatible, making this an effective and safe anti-aging solution. However, some mild temporary side effects may occur, including inflammation, rash, itching, pain, or discomfort at the injection site. These reactions typically appear immediately or shortly after treatment, and will resolve themselves within a few days. The solution is contained in 5 ml vials and can be injected into the skin of the face, neck, decolletage, and the back of the hands on patients between the ages of 20 to 40.

Suggested Usage

The suggested directions for use are as follows:

  • Pluryal Meso I can be used to treat the face, neck, decolletage, and the back of the hands.
  • Inject the solution into the treatment area in a series of microinjections into the surface layer of the skin. A mesotherapy gun, an automatic injector, or a fine needle can be used.
  • Massage the treated area once injection is completed in order to distribute the solution evenly.
  • Treatment should be administered across 3 phases. Phase 1 takes place over 4 sessions taking place 1 week apart. Phase 2 includes 2 sessions administered in monthly intervals. Phase 3 involves maintenance sessions occurring every 2 to 6 months depending on the results experienced by the patient. 


Pluryal Meso I is composed of hyaluronic acid fragments, which provide an effective hydrating effect that results in added volume and rejuvenation. The formula also includes sodium bicarbonate and an amino acid complex made of L-isoleucine, L-leucine, L-lysine hydrochloride, L-proline, L-valine, glycine, L-serine, L-alanine, L-cyteine.

What is in the box

Each box of Pluryal Meso I contains the following:

  • 3 vials of 5 ml of solution
  • 2 traceability labels
  • Device manual insert

Duration of effect

Like all dermal fillers, the duration of effects will vary by patient depending on a number of factors including the age and lifestyle of the individual, the injection technique used and the area being treated. However, on average, patients typically experience results from 2 to 6 months after the initial treatment is completed.

Storage conditions

Pluryal Meso I should be stored in the original box and handled with care. The package should be kept in a dry place between the temperatures of 2° C and 25° C where it will not be subjected to light, heat, or frost. If the product is stored improperly, the solution may break down and become compromised. Always check the packaging prior to use to ensure the solution has not been tampered with.

Expiry (shelf life)

  • Always check the expiry date printed on the product label. Do not use the solution if the expiry date has passed