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Stylage and Juvederm are brands of hyaluronic acid based dermal fillers. Stylage is developed and produced by Vivacy Laboratories, a global pharmaceutical company based in France. Juvederm, on the other hand, is a product of the Dublin-based Allergan. Stylage has been approved for use in the United Kingdom since 2011.
The Stylage collection consists of Stylage S, Stylage M, Stylage L, Stylage XL, Stylage XXL, Stylage Special Lips, Stylage Hydro and Stylage Hydromax. Some of the most popular Juvederm products include Juvederm Ultra, Juvederm Ultra Plus, Juvederm Voluma, and Juvederm Vollure. In this article, we will review the similarities and differences between Stylage and Juvederm in terms of their uses, active ingredients, durability and prices.Stylage fillers are designed to address a wide range of aging concerns. For instance, Stylage can help to fill and smooth wrinkles. They are especially effective in the treatment of superficial wrinkles and fine lines, including cheek wrinkles, glabellar frown lines, marionette lines, perioral lines, crow’s feet and nasolabial folds (furrows extending from the angle of the mouth to the base of the nose). Plus, Stylage can be used under the eyes for the treatment of tear trough area. Similarly, Juvederm is indicated for the correction of moderate to severe facial wrinkles and folds such as nasolabial folds. Stylage can also be used on the hands for the treatment of volume loss.
Stylage products are also perfect for volume restoration and facial remodeling. In particular, Stylage XL and Stylage XXL help restore facial contours and replenish the lost volume of the face. Apart from augmenting the cheekbone area, Stylage fillers effectively treat mild to severe skin sagging (medically known as facial ptosis). Voluma XC is Juvederm’s answer to age-related volume loss. Fortified with volumizing ingredients, it helps adult patients to increase the volume in the cheek area for a youthful appearance.
Stylage fillers such as Stylage Hydro and Stylage Hydromax have the added benefit of bio-revitalization and skin hydration. In particular, Stylage Hydro is able to improve skin elasticity and revitalize the neck and decollete, backs of the hands, and face. It also helps to treat skin dehydration of moderate severity (for severe dehydration, it is recommended to use a stronger formulation such as Stylage Hydromax). Similarly, Juvederm Hydrate is also used to improve skin hydration, elasticity, and skin tone. This injectable is used for the face, neck, and backs of the hands.
Stylage fillers are formulated with cross-linked hyaluronic acid and mannitol. Manufactured using the innovative IPN-Like Technology, the hyaluronic acid in Stylage consists of two distinct structures, which are the IPN-Like structure and the monophasic A and B structure. These structures are designed to be mechanically independent of each other. Thanks to the cutting edge manufacturing technique, Stylage has an increased density of the cross-linking nodes, therefore is longer lasting. At the same time, the unique structure allows for easy injection. The patented manufacturing method involves less amount of BDDE, which is a compound commonly used for cross-linking. This contributes to the enhanced safety profile and durability of Stylage.
Mannitol is a natural compound found abundantly in fruits and vegetables such as raspberries, olives, and celery. Known to have strong anti-oxidative properties, mannitol effectively reduces the adverse reactions of hyaluronic acid such as swelling and redness. Aptly named the free radical scavenger, mannitol helps limit the harmful effects of free radicals on the injected product and on the dermis, thereby minimizing the risks of injection-related inflammation. At the same time, it prevents the degradation of hyaluronic acid by the body.
Juvederm is made of cross-linked hyaluronic acid derived from a non-animal source. Having a non-animal origin means that it is unlikely to cause any immunogenic reactions. Thanks to patented cross-linking technologies used in the manufacturing process), Juvederm is significantly more durable than other fillers on the market. The durability of the fillers will be discussed in depth in the following section.
Many Juvederm and Stylage formulations are infused with lidocaine, an anesthetic that inhibits voltage-gated sodium channels and blocks ionic fluxes. By inducing local anesthesia. Juvederm effectively reduces pain and discomfort associated with the injection process, making the treatment virtually painless.
For Stylage, the duration of action varies greatly among products. As claimed by the manufacturer, Stylage cosmetic injectables can last between 6 to 12 months. Each filler in the collection has an average duration time specified by the manufacturer.
The durability of Juvederm fillers also ranges. Depending on the filler used, Juvederm can last from 3 months to 2 years.
Keep in mind that the figures are only a rough estimate. The actual duration of action can be affected by a wide range of factors such as age, lifestyle, skin structure and skin type. As well, the rate of metabolism can affect the rate at which hyaluronic acid is degraded. These factors tend to vary greatly from patient to patient, making it impossible to determine the length of action accurately. Aside from that, the injection technique and location of treatment area also have an effect on product longevity.
Each filler brand has its own advantages and disadvantages. As well, each patient is unique and has different needs. When choosing between Stylage and Juvederm, doctors should consider the indications treated, durability, treatment cost and other important factors.
Disclaimer: These articles, and any views and opinions expressed, are not endorsed by Raskel Medical. The articles are strictly for informational purposes and should not be considered medical advice. Raskel Medical does not check or edit the content of these articles for medical accuracy. Contact your medical practitioner for any medical advice needed.