Botox for Penis: Procedure, Treatment, Results & Benefits

When we think of Botox, wrinkles and lines are often the first things that come to mind. Having potent muscle relaxant properties, Botox is conventionally used to reduce aging signs such as forehead lines, glabellar lines and lateral canthal lines (or more commonly known as crow's feet). At the same time, it is used clinically to treat a wide range of medical conditions such as spasticity, overactive bladder, migraines, blepharospasm, urinary incontinence and cervical dystonia. Botox injections are often used off label for both aesthetic and medical purposes. This includes the treatment of acne, TMJ syndrome, hyperhidrosis (excessive sweating), and last but not least, penis enhancement. Plus, Botox seems to be a promising treatment for premature ejaculation.

Botox for penis: a case of serendipity

Scientists were not necessarily looking for ways to enhance the size of penis. In fact, the penis-enlarging properties of Botox are discovered accidentally. In a study published in the Journal of Sexual Medicine, Botox injections were administered to the base of the penis to treat hyperactive retraction reflex (a medical condition that causes the penis to retreat when the patient is stressed out or cold). Through muscle paralysis, Botox successfully prevents the penis from withering in cold conditions. More importantly, researchers discovered a valuable side effect—the length of the flaccid penises was increased by half an inch. This is when doctors realized that Botox can be used as a penile lengthening treatment. Keep in mind that Botox has no effect on the size of an erected penis.

Who should use Botox for penis?

Various studies have found that a large proportion of men are insecure about their penis size. While the idea of Botox penile injections might sound bizarre, a lot of male patients are willing to have Botox injected in their penis, as long as it works. After all, many of them have resorted to questionable and sketchy treatments in the pursuit of a superior penis size (think penis weights, pumps, and an exercise known as jelqing). Some of these penis-enhancing treatments have not been scientifically verified, thus can be potentially dangerous. Botox offers a considerably safer way of enhancing the penis. From erectile dysfunction to penis enlargement, Botox is effective for almost all phallic imperfections. It also appears that Botox has a positive effect on sexual performance, helping patients to last longer in bed. This makes Botox suitable for patients who suffer from premature ejaculation.

Botox injections are especially useful for patients who are unable to take erectile dysfunction drugs such as sildenafil (or more commonly known as Viagra). While reasonably effective, Viagra may interact with many other medications, including (but not limited to) calcium channel blockers, HIV protease inhibitors, macrolide antibiotics, aripiprazole, azole antifungals, amiodarone, phosphodiesterase 5 inhibitors and statins. In particular, Viagra is contraindicated in patients who are on nitrate medications such as isosorbide dinitrate and nitroglycerin. Botox serves as the perfect alternative for these patients.

How does Botox for penis work?

Botox is formulated with botulinum toxin type A, a type of neurotoxin that has muscle relaxant effects. The science behind Botox is fairly simple: it inhibits muscle contractions. Once administered, Botox will bind to the motor nerves (or more specifically, the cholinergic receptors) to inhibit the release of acetylcholine, a type of neurotransmitter that plays a role in muscle contractions. This subsequently leads to decreased muscle activities. When used for wrinkle treatment, Botox is able to prevent the contraction of underlying muscles (which is known to cause surface wrinkles). In this case, Botox helps to relax the penile muscles, thereby promoting blood flow.

In an animal study, Botox has been shown to significantly enhance the sexual performance of rats. Compared to control group, rats that have had Botox injection are able to last for 3.5 minutes longer before ejaculating. Having dramatic sexual enhancing effects, Botox is poised to revolutionize the treatment of premature ejaculation. Premature ejaculation occurs when the patient is ejaculating too soon (typically less than 1 to 3 minutes). While highly prevalent, premature ejaculation is often poorly managed. The treatments are not always effective, and it usually takes a combination of different treatments to see results. It is believed that Botox exerts an inhibitory effect on the bulbospongiosus muscle (which controls ejaculation and erection) to delay ejaculation.

How long can the results last?

Botox for penis can generally last for 4 to 6 months, after which the results will disappear. Repeat treatments are required to maintain the results.

Is Botox for penis safe?

When used correctly, Botox for penis is generally safe and well tolerated. Botox is not known to migrate from the injection site. In other words, Botox will remain localized to where it is injected. Having said that, Botox could travel up to 3cm from the point of injection.

Botox is unlikely to cause numbness. This is because Botox only acts on motor nerves and does not affect muscles that control sensation.

Practitioners should be extra cautious while performing the treatment to minimize the risk of side effects. Prior to the injection, patients should be made aware of the fact that Botox is being used off label. Patients should only proceed with the treatment if they find the potential risks acceptable. While the findings from clinical trials are mostly positive, side effects such as prolonged erection have been reported.

To ensure patient safety, it is not advisable to use Botox in patients who have known allergy to botulinum toxin or any other inactive ingredients in the formulation. In general, Botox is intended for adult patients of more than 18 years of age (except when used in the treatment of lower limb spasms).