Are Expired Injectables Harmful?

Are Expired Injectables Harmful?

You will learn:

  • Are Expired Injectables Harmful?
  • Should injected dermal fillers be used?
  • Will expired dermal fillers dissolve?
  • Should I report it if my doctor uses expired dermal fillers?
  • Is it okay for a doctor to use Restylane or other dermal fillers that are about to expire?

Is it safe to inject an unopened box of expired dermal fillers? Will the product last?

Dermal fillers are gel-like substances that are injected into the skin to correct certain skin concerns, such as lines and wrinkles. Soft tissue filler injections are considered medical treatments that should only be conducted by a certified physician. Since the procedure involves intradermal administration, it is extremely important that the treatment is conducted with strict adherence to aseptic medical standards, so as to reduce the risk of immunogenic responses. Equally important criterion is the shelf life of the dermal filler. The expiry date determined by the manufacturer guarantees that the sterility and the quality of the implants last up until the expiration date. Using expired dermal fillers may lead to reduced potency and safety of the post-treatment results. Besides that, expired soft tissue fillers may only deliver aesthetic results for a shorter period of time compared to dermal fillers with a much longer shelf life.

What Makes Dermal Fillers the Best Solution for Skin Rejuvenation?

Would expired fillers be okay as it dissolves with time?

Most dermal fillers are composed of biodegradable materials like hyaluronic acid, collagen, poly-L-lactic acid (PLLA), and calcium hydroxylapatite. These bioresorbable fillers will be gradually metabolized by the surrounding tissues, and the residence time of these implants depend largely on a patient’s health, severity of skin condition, and lifestyle choices. Once the injected fillers start to resorb, the patient’s aesthetic corrections will reverse over time. Though this is an expected process, expired fillers may not product effective results. Not only could the expired soft tissue fillers fail to correct the aesthetic imperfections adequately, the fillers may also be disintegrated at a much quicker rate compared to implants with longer shelf life. In addition, expired injectable fillers are also deemed medically unsafe as they are more susceptible for inducing inflammatory infections and immunogenic reactions.

My doctor injected cosmetic fillers that had been expired. Should this be reported?

Patients are strongly recommended to make informed decisions prior to obtaining dermal filler injections. The Food and Drug Administration (FDA) recommends reviewing the following checklist prior to receiving cosmetic injectables.

Approved and Unapproved Uses of Soft Tissue Fillers (Cosmetic Injectables)

  • Patients should always work with qualified and highly experienced physicians who only use properly labeled, sealed vials for treatments. They are also free to inquire more about their doctors’ experience in injecting implants.
  • Patients must always know the type of injectables to be implanted and all of its possible side effects. An initial consultation session should be reserved for discussing medical history, the aesthetic treatment, dermal filler of choice, the possible side effects, and precautions. Patients are always allowed to request and read the patient labeling information on injectable implants prior to undergoing the treatment session.
  • It is very important that patients do not receive dermal filler injections from unlicensed providers.

Patients who have been injected with an expired filler can report it to a regulatory agent in their area, such as the FDA.

Is it okay for a doctor to use Restylane or other dermal fillers that are about to expire?

There is currently no clinical evidence regarding the safety of injecting dermal fillers that are about to expire. If you are considering treatment with dermal fillers, ensure that you seek treatment with a licensed injector. This will help reduce the risk of adverse effects that can occur when being injected by an unlicensed and untrained individual. Your doctor will determine the best course of treatment for you.

More Information

Dermal Filler Checklist: Physicians and Patients

What Makes Dermal Fillers the Best Solution for Skin Rejuvenation?

Can Patient Lose Dermal Fillers Due to Weight Loss?

Disclaimer: These articles, and any views and opinions expressed, are not endorsed by Raskel Medical. The articles are strictly for informational purposes and should not be considered medical advice. Raskel Medical does not check or edit the content of these articles for medical accuracy. Contact your medical practitioner for any medical advice needed.