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Manufacturer: Solstice Neurosciences
Active Substance(s) : Botulinum toxin type B
Strength: 5,000U
Pack Size: 1 vial
Accessories: Package Insert

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Product: NEUROBLOC® (MYOBLOC®) 10000U
Manufacturer: Solstice Neurosciences
Active Substance(s) : Botulinum toxin type B
Strength: 10,000U
Pack Size: 1 vial
Accessories: Package Insert

Sorry, this item is out of stock

NeuroBloc® (Myobloc®) Product specifications

NeuroBloc, also known as Myobloc, is an injectable medical device made of the neurotoxin botulinum toxin type B. It is a clear solution that is colorless to yellow in appearance. It is a muscle relaxant and is only available by prescription. It should only ever be administered by a licensed medical professional.

What NeuroBloc (Myobloc) is formulated to do

NeuroBloc is indicated for use in the treatment of cervical dystonia in adults and relieve pain in the neck and shoulder area. Botulinum toxin type B, the active ingredient, is a neurotoxin that blocks activity in the nerves, preventing the release of acetylcholine, which transmits signals to the brain that tell the muscles to contract. Upon injection, there is a temporary muscle paralysis, making this a great treatment for conditions that involve muscle spasms such as cervical dystonia. It functions similarly to botulinum toxin type A, which is the active ingredient in other types face injections like Botox and Dysport. If botulinum toxin type A loses its efficacy for a patient, as it has a tendency to over time, they may turn to botulinum toxin type B for more effective treatment. It is the only formulation of type b botulinum toxin in the world that is currently approved for use.


Solstice Neurosciences, a subsidiary of US WorldMeds, manufactures and distributes NeuroBloc. It is available under the name Myobloc in the US but is sold as NeuroBloc elsewhere in the world.

The botulinum toxin type B included in this formulation is purified and produced by Clostridium botulinum, a bacterium that is typically found in soil.

What else you need to know

Though NeuroBloc is not currently approved for cosmetic use, some medical practitioners may use this injectable to temporarily lessen the appearance of lines and wrinkles, particularly the glabellar lines that appear between the eyebrows. The solution became available in the UK in 2001 and was approved by the FDA in December 2000 for the treatment of cervical dystonia. Just as with most treatments requiring dermal injection, there are some side effects associated with injection. These include headache, dry mouth, and reactions like pain, bruising, or swelling at the injection site. Though rare, more serious reactions may occur, such as difficulty swallowing, speaking, or breathing. If these adverse effects present themselves, patients should seek immediate medical assistance.

Suggested usage

The suggested directions for use are as follows:

  • An initial dose of 10,000 units should be divided into 2 to 4 injections into the muscles that are most affected. To divide the total dose between multiple injection sites, you may use sodium chloride 9mg/ml to dilute the solution. The diluted solution should be used immediately.
  • NeuroBloc should be injected intramuscularly into affected muscles, being careful not to inject into a blood vessel.

Refer to the product pamphlet for additional information.


NeuroBloc is composed of Botulinum toxin type B, with each ml containing 5,000 units of the neurotoxin. The solution also includes the excipients disodium succinate, sodium chloride, human serum albumin, hydrochloric acid for pH adjustment, and water.

What is in the box?

Each box of NeuroBloc contains the following:

  • 1 vial of solution;
  • Product information leaflet.

Duration of effect

The duration of effect will vary by patient depending on a number of factors, including the age and lifestyle of the individual, as well as the injection area and the injection technique used. However, on average, result last approximately 3 to 4 months after initial treatment. Patients can receive injections every 12 weeks, depending on the dosage requirements, to maintain results. Injectors may need to adjust the dose depending on how the patient responds to treatment. It is recommended to wait a minimum of 3 months for maintenance treatments; however, some doctors administer “touch-up” treatments prior to this if the initial dose is not enough.

Is NeuroBloc FDA approved?
Known as Myobloc in the US, this botulinum toxin injectable is has been FDA approved since 2000.

Storage conditions

NeuroBloc should be stored in its original packaging to protect from sunlight, and should be stored in a refrigerator at 2°C–8°C. This injectable should not be frozen, though it may be removed from refrigeration once for a period of 3 months and kept in a temperature under 25°C but it must not be refrigerated again. If you dilute the solution, you must use it immediately.

Expiry (shelf life)

  • The shelf life of this product is expected to last for 5 years from the date of manufacture. Please note that improper storage conditions may affect the shelf life of the toxin.
  • Always check the expiration date printed on the product label prior to use. Do not use if it is passed the date of expiration.