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Juvederm Ultra 2 is a dermal filler made of cross-linked hyaluronic acid (HA) used to treat moderate to severe facial wrinkles and folds and to provide lip definition. This biocompatible filler gives immediate, natural looking results. A local anesthetic, lidocaine hydrochloride, is added to improve tolerability and overall patient’s comfort. Hyaluronic acid is a naturally occurring substance in the body that lubricates joints and hydrates the skin. By retaining moisture, it fills moderate lines and skin depressions to reveal a smoother and more rejuvenated skin.
What Juvederm Ultra 2 is formulated to do
This facial filler is specially formulated using the patented Hyalacross process to create hyaluronic acid molecules with a smoother or more homogenized consistency. When injected intradermally, it replenishes the diminishing levels of HA in the skin. Aside from boosting hydration, Juvederm Ultra 2 can also replace volume loss and improve the look of hollow, sagging skin. It also helps plump the lip area for a more defined look.
Manufactured by Allergan
What else you need to know
Common side effects associated with the treatment
Treated patients reported transient side effects that lasted within a day or two for facial injection, and up to a week for lip injection. The most common side effects reported are as follows:
Which skin type is it good for?
Juvederm Ultra 2 is a safe and effective dermal filler for patients of various skin types. It works best on dry, dull skin, with medium lines and folds. It significantly improves the appearance of marionette lines, nasolabial folds, and frown lines. It is also approved to be injected on the lips to plump and contour a less defined lip outline.
Precautions and contraindications
This medical-grade filler has been subjected to various clinical studies and trials to verify its safety and efficacy. It is contraindicated in the following group of individuals:
- Patients under the age of 21.
- Patients with known hypersensitivity to any components of the medication (e.g. bacterial proteins and lidocaine)
- Pregnant and breastfeeding women
Juvederm Ultra 2 is a gel filler that comes in a pre-filled syringe. Check the integrity of the gel solution and needles prior to injection. The content must appear transparent without visible particulates.
- Juvederm Ultra 2 must be injected into the dermis or the mucous membrane of the lips.
- The product must be used as supplied following proper aseptic technique.
- Using the 30G ½” needle provided, slowly inject into the mid dermis.
- Massage the treated area to ensure even distribution of the product.
Juvederm Ultra 2 contains cross-linked hyaluronic acid that is biodegradable. It is formulated to a concentration of 24mg/ml, while the additional Lidocaine is at 0.3%.
What is in the box
- Two pre-filled 0.55ml syringes
- Two 30 G 1/2 needles
- Four traceability labels
- Package Insert
Duration of effect
The immediate and long-lasting results from this filler consistently satisfy both patients and practitioners. The positive effects of Juvederm Ultra 2 may last for up to 12 months. Each patient may experience longer or shorter duration depending on their lifestyle, age, and areas treated.
It must be kept in a cool, dry place, away from direct sunlight to maintain the integrity of the medication. Store between 2℃ and 25℃. Do not freeze.
Expiry (shelf life)
- The unopened vial, when kept in its original packaging, remains viable up to 24 months.
- Do not use past the expiration date in the package.