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Manufacturer: Allergan
Active Substance(s) : Hyaluronic acid, mannitol
Strength: 13.5mg/ml, 9mg/ml
Pack Size: 1-1ml prefilled syringe
Accessories: Package insert, 2-30G 1/6” needles, 2 traceability labels

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Juvederm Hydrate is a medical-grade filler that serves as a hydrating agent to combat skin dryness, dehydration, and fine lines. It is made of sterile, apyrogenic, non-animal hyaluronic acid (HA) in a physiological gel solution. The natural antioxidant mannitol is added to decrease the damaging effects of free radical and prolong the results of the treatment. HA is extremely effective in providing deep hydration by attracting water molecules deep within the cells. The focus of this treatment is replenishing depleted levels of hyaluronic acid, restoring elasticity in the skin, and revealing a natural, healthy glow by boosting skin hydration.

 What Juvederm Hydrate is formulated to do

Juvederm Hydrate is specially formulated to counter the negative effects of sun damage, natural aging, and other environmental deterrents. It addresses various skin problems such as dry, dull skin. It can be safely administered on the face, neck, decollete, and back of hands.

This particular variant is not indicated for volume creation and correcting deep wrinkles. There are other Juvederm products that are specifically intended to treat the conditions mentioned. Juvederm Hydrate, on the other hand, is the most effective filler for retaining moisture within the skin. We all know the importance of keeping the skin hydrated to make it appear smooth and elastic. Hyaluronic acid improves an uneven and rough skin texture by providing maximum hydration. As water fills the gaps under the skin, it creates slight plumping and smoothing effect that is more subtle and natural looking.


Manufactured by Allergan


Dublin, Ireland

What else you need to know:

  • Common side effects associated with the treatment

The Juvederm collection of dermal fillers has been studied extensively to test for its safety and efficacy. These research studies and actual patient administration reported the following side effects that are often experienced after Juvederm Hydrate injection. This non-exhaustive list of post-injection reactions may last for a couple of days or up to a week.

  • Inflammatory reactions: redness, swelling, itching, and pain
  • Discoloration at the injection site
  • Induration or nodule formation
  • Which skin type is it good for?

This injectable works for all skin types, especially those that lack moisture, with a rough or dull texture. By drawing in and retaining moisture, it reveals a smoother, brighter, and more even complexion. It’s perfect for those with mild or moderate skin concerns that are just experiencing the first signs of aging.  

  • Precautions and contraindications

Juvederm Hydrate is a mesotherapy injectable, which contains hyaluronic acid and the antioxidant mannitol. Both ingredients are proven safe and effective when injected into the dermis. HA is a naturally occurring substance in the body, thus pre-testing is not required for this treatment. It is not recommended for patients with a history of multiple allergic reactions or anaphylactic shock. Pregnant or breastfeeding women should not be given this treatment.

  • Awards and certification

Juvederm products are approved by the US FDA and awarded certifications as medical devices for correcting moderate to severe wrinkles and contouring the lips of patients over the age of 18.

  • Packaging information

Juvederm Hydrate is a transparent and viscous gel presented in a graduated prefilled syringe for single use. Check the integrity of the gel solution and needles prior to injection. Do not use if the content of the syringe appears cloudy or if the packaging is not intact.

Suggested Usage

  • This filler is safe to be injected intradermally into the face, neck, decollete, and backs of hands.
  • Remove all traces of makeup and dirt in the patient’s skin, and disinfect the area using suitable antiseptic solution.
  • Using the sterile needle provided, inject the filler beneath the upper layer of skin about 1–2cm apart.
  • The amount to be injected depends on the areas to be treated and the patient’s desired results.
  • Massage the treated area if necessary.
  • Do not repeat the treatment at less than a 15-day interval.


Juvederm Hydrate contains 13.5mg/ml hyaluronic acid in a purified, physiological solution with phosphate buffer pH 7.2 q.s.p. It also contains 9mg/ml of mannitol—an antioxidant that attacks free radicals to prevent the degradation of HA.

What is in the box

  • 1 sterile pre-filled syringe containing 1ml solution
  • 2 sterile single-use 30G needles
  • A set of traceability labels and instruction leaflet

Duration of effect

Over a period of months, the hyaluronic acid filler is completely absorbed within the skin, leaving no trace of the filler. The average duration for this cosmetic injectable is between 4 to 6 months.

Storage conditions

Protect the packaging from freezing temperatures and extreme heat. Store at a temperature between 2℃ to 25℃.

Expiry (shelf life)

  • The unopened vial, when kept in its original packaging, can be stored up to 2 years.
  • Use prior to the expiration date in the package.