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NeuroBloc® (Botulinum Toxins type B)

What are the products by this brand?

NeuroBloc, also known as Myobloc, is an injectable solution made of botulinum toxin type B that is manufactured by Eisai Ltd. The toxin is harvested from fermenting Clostridium botulinum bacteria Bean strain, which is then purified to remove any harmful contaminants.

This toxin exists as an injectable solution that can be readily administered into affected muscles. However, only legally certified physicians who are familiar with handling botulinum toxin preparations safely should conduct medical procedures using this product.


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Due to its unique preparation, NeuroBloc is a popular toxin for those who are resistant to botulinum toxin type A. As well, numerous studies show this neuromodulator is fast-acting and long-lasting, making it an obvious treatment choice for those experiencing cervical dystonia.


How long has it been on the market?

This injectable solution has been made available for commercial use in the UK since 2001. Since then, it has become widely used in type A-resistant patients.


How does it work effectively?

When the motor skills function just as intended, impulses are sent to the muscles for movement, resulting in actions such as running and typing. Unfortunately, some medical incidents, like a stroke, could disrupt the normal transmission of impulses and can cause neurological disorders like cervical dystonia, which is marked by painful contractions of the neck. If left untreated, patients could suffer greatly from decreased quality of life.

NeuroBloc consists of botulinum toxin type B to specifically treat cervical dystonia in patients below 65 years of age. The neurotoxins bind to receptors on neuromuscular junctions and proceed to inhibit the release of acetylcholine—a type of chemical impulse. The injected muscles are then temporarily paralyzed resulting in obvious improvements of cervical dystonia.


What are the active ingredients that make the brand unique?

NeuroBloc is the only preparation that contains botulinum toxin type B. The neurotoxin is extracted from fermenting Clostridium botulinum bacteria, Bean strain, which is then thoroughly purified to remove harmful contaminants. This is especially useful for patients who cannot receive treatment with type A injectables.


Why is it different from other brands?

Not only is it the only brand that contains botulinum toxin type B, NeuroBloc also exists as an injectable solution that can be easily administered in patients suffering from cervical dystonia. The preparation is unique for the optimal treatment of neck spasms (cervical dystonia), and improvements may last up to 16 weeks of longer. Dosing frequency is adapted based on the individual needs of your patient.


What skin type is it suitable for?

NeuroBloc is specially formulated to treat cervical dystonia, a neurological disorder affecting the neck. That being said, due to its preparation, it cannot be used interchangeably with other botulinum toxin injectables. It is safe for use on most skin types, including those who are type A-resistant.


What are some of the side effects?

Patients may exhibit some aftereffects after obtaining treatment, including injection-related inflammatory responses.

Common side effects:

  • Injection site pain
  • Difficulty swallowing
  • Indigestion
  • Dry mouth
  • Headache

Discuss all possible side effects with your patient and any necessary treatment options prior to the procedure.

Rare side effects:

  • Spread of toxin, with symptoms including exaggerated muscle weakness or aspiration pneumonia

These may not be the only adverse reactions. Read the product pamphlet for a detailed list of probable side effects.


Why should you choose this brand?

NeuroBloc is a localized muscle relaxant that has been specifically formulated to manage symptoms of cervical dystonia. It is also the only brand of botulinum preparation that contains of botulinum toxin type B.

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