Dermal fillers complete guide

Are dermal filler injection treatments safe?

Dermatologists, plastic surgeons, and other doctors have been using dermal fillers for decades now with much success. This form of aesthetic anti-aging treatment, though not permanent, is much less invasive and is much safer than many surgical options that help patients achieve smoother, younger looking skin.


  • How do you know if it is safe?

    Dermal injectables are considered medical devices, and are therefore regulated by overseeing bodies such as the FDA in the United States and the CE in the European Union. That means that the facial fillers undergo clinical testing and have publicly available certification that consumers can look to for more information on safety. Additionally, many fillers contain ingredients that are very biocompatible, meaning there is a very low risk of adverse reactions occurring.


  • What makes filler long lasting and safe?

  • Facial fillers are specially formulated for long-lasting effects, with some product ranges even including antioxidants and other nutrients that help to fight off free radicals. By fighting free radicals, these ingredients help to slow down the process of metabolization, allowing the filling ingredient—which is typically hyaluronic acid in temporary facial fillers—to last longer.


    Fillers are also so safe because they typically only include active ingredients that are naturally occurring within the human body, but that the body has stopped producing as quickly because of the aging process. This leads to a high level of biocompatibility. Additionally, dermal fillers are typically manufactured with the highest standards of safety in mind, giving most of the facial injections on the market a high safety profile.


For more information see the checklist below.

Checklist: Check before you inject:

  • #1

    Know what filler you are being injected with and whether or not it is approved by the FDA or other regulatory agents.
  • #2

    Speak to a health-care professional about the risks, contraindications, and common side effects associated with the dermal filler you are being injected with.
  • #3

    Only get injections from a licensed health-care provider and ask them about their experience injecting facial fillers.
  • #4

    Know which fillers and situations to avoid, such as receiving fillers from an unlicensed practitioner or in a non-medical setting.
  • #5

    Ask about the average duration of an injection session and any expected downtime you may experience after treatment.
  • #6

    Discuss your medical history with the administering health-care professional to ensure you are eligible for injections with the chosen cosmetic injectable.


How to Minimize Risks and Increase Good Outcomes for All Wrinkle Fillers

  • Don't be lured by a low price. Price should not be your guide when choosing the right filler—if you find a filler that is much lower than the standard price, it is likely due to a subpar product or an inexperienced practitioner. Remember that facial filler injections are a medical procedure and should not be a bargain-bin purchase.

  • Only receive wrinkle fillers in a medical setting with sterile instruments. Injections administered in homes, hotels, or resorts are not as trustworthy as medical offices.

  • Ask your doctor about information about the filler you are being injected with, and double check with your doctor to make sure it is FDA-approved. Do not proceed with injections if your provider is not forthcoming with this information.

  • Discuss any suggestions for aftercare with your doctor and follow his/her advice. Apply sunscreen daily following procedure in order to prevent post-injection pigment changes and to help maintain results of the filler for longer.


Natural vs Synthetic Cosmetic Fillers

Cosmetic fillers are available using either natural or synthetic ingredients, and your doctor may recommend using either of these varieties of fillers to perform specific desired effects. Whether you receive a natural or synthetic filler, both categories of dermal fillers are only temporary and not permanent.


What are Natural fillers?

Natural fillers are those that are created with ingredients that come from natural sources, such as human bodies or animals. The ingredients used are typically proteins or even fats.


Material used:

Collagen is one of the most popular natural materials used in dermal fillers, as it is a protein that helps maintain firmness and elasticity in the skin’s structure. For facial fillers, collagen is typically derived from human, cow, or pig sources. Fat from the patient’s own body can also be used as a more permanent filler treatment option and is considered a natural material. For this method of filling, excess fat is typically taken from the thigh or stomach area and displaced into the face. Hyaluronic acid is also a popular material used in facial fillers, and it is possible to formulate the hyaluronic acid from animals. In these instances, it is typically harvested from the combs of roosters.


Types of natural dermal fillers
  • Collagen-based (and therefore natural) dermal fillers include Zyderm/Zyplast, Cosmoderm/Cosmoplast, and Evolence.
  • Hylaform is an example of an animal-derived hyaluronic acid filler.


What are Synthetic fillers?

Synthetic filler are those that use ingredients that are man-made, with the material typically being produced in a laboratory.

Material used

Though hyaluronic acid is found within the human body and can be derived from animals, dermal fillers most commonly use hyaluronic acid of non-animal origin. To produce this, companies use a process of bacterial fermentation within a lab setting. Poly-L-lactic acid is another synthetic material used in dermal fillers, as it helps the body produce collagen. Calcium hydroxylapatite is yet another material that is found naturally within the body, but is produced biosynthetically when used in fillers.


Types of Synthetic dermal fillers



Facial filler injections are a closely regulated field of cosmetic medicine, for which products must undergo testing and receive approval from regulating organizations before becoming available to the public. So long as you receive brand name injections from a trusted medical professional, you will be perfectly safe receiving facial filler treatment to halt and correct the signs of premature aging or other skin imperfections.

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Disclaimer: These articles, and any views and opinions expressed, are not endorsed by Raskel Medical. The articles are strictly for informational purposes and should not be considered medical advice. Raskel Medical does not check or edit the content of these articles for medical accuracy. Contact your medical practitioner for any medical advice needed.