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Manufacturer: Merz Pharmaceuticals
Active Substance(s) : Sodium hyaluronate
Strength: 18mg/ml
Pack Size: 1-1ml prefilled syringe
Accessories: Package insert, 2-30G 1/2
You can save $60.00 if you add an additional 5 units to your cart.

Product specifications

Belotero Hydro is one of many dermal fillers in the Belotero product range. It provides deep hydration that allows skin to appear invigorated and youthful. Through superficial microinjections, this entry-level injectable gel rejuvenates the skin and leaves long-lasting moisturization for optimal skin maintenance. With a special formula consisting of glycerol and hyaluronic acid, this dermal injection provides targeted rehydration that adds elasticity and radiance to the skin. Furthermore, this cosmetic injectable can help reduce the appearance of the early signs of aging and prevent further damage to the skin. 

What Belotero Hydro is formulated to do

This injectable solution is formulated to moisturize the skin on a deep level and improve skin health by improving elasticity. Belotero Hydro’s active ingredients are 18mg/ml of hyaluronic acid of non-animal origin and glycerol. The hyaluronic acid is manufactured via Dynamic Cross-Linking Technology, which has 2 added phases compared to standard cross-linking technology. These extra phases allow the gel to crosslink twice and fill out any gaps with additional non-crosslinked molecules. Overall, this process creates cohesive, malleable gel that integrates seamlessly within the dermis and is suitable for all skin types. Upon injection, this filler can diminish the signs of aging and can help improve the look of sun spots and dull, dehydrated skin. It can also volumize skin and fix the color and tone in the treated areas.   


Belotero Hydro is manufactured by Merz Aesthetics. This product was introduced in April 2014.

This product is manufactured in Europe.

What else you need to know

What skin type is it good for?

Belotero Hydro is suitable for all skin types, and due to the fact that it is made with ingredients that are naturally-occurring, it is incredibly biocompatible and safe.

Is it tested by dermatologists?

In fact, this dermal rejuvenation product is popular with dermatologists around the globe.  It is important to note that while other products in the Belotero range of injectable dermal fillers are most suited for volume restoration and for smoothing and filling lines and wrinkles, Belotero Hydro is unique in that it is intended as a deep hydrating treatment for the skin.

When it can cause side effects

It is also important to advise patients that they may experience temporary side effects as a result of treatment, including bruising, swelling, redness, itching, tenderness, and discoloration. These typically appear immediately or shortly after the patient receives the facial injections and will resolve themselves within a few days without intervention. This may not be a complete list of side effects. Refer to the package insert for a full list of side effects, warnings, and contraindications. If any adverse effects are prolonged or worsen, your patient should contact you or another medical professional.

The aesthetic gel comes in a prefilled syringe that contains 1ml of solution.

Suggested usage

The suggested directions for use are as follows:

  • Patients should be informed of all possible side effects, contraindications, and precautions prior to treatment. Informing patients about such information is necessary to legitimately obtain their informed consent.
  • Belotero Hydro should be administered by dermal injection into the superficial dermis via microinjections.
  • This rehydrating treatment should only be used on the face, neck, décolletage, and hands.
  • 2 to 3 treatment sessions carried out with 2 to 3 weeks between each session is recommended for the initial treatment stage.
  • Maintenance treatments can be given once or twice a year following the initial treatment.


This dermal injection is composed of 18mg/ml of hyaluronic acid and 21mg/ml of glycerol in a physiological phosphate-citrate buffer of pH 7. The injectable gel is sterile, non-pyrogenic, viscoelastic, and provides optimal results to patients while maintaining a natural look and feel to the face.

What is in the box

Each box of Belotero Hydro contains:

  • 1 prefilled syringed with 1 ml of gel
  • 2-30G ½” sterile needles
  • Package insert
  • Traceability labels

Duration of effect

The duration of effect will vary on a patient-by-patient basis, depending on a number of factors, including a patient’s age and lifestyle, the area being treated by the skin filler, and the condition of the skin. However, on average, the results are expected to last for approximately 6 months to a year, after which patients may receive additional maintenance treatments to prolong the effects.

Storage conditions

Belotero Hydro comes in sterile packaging and should be stored in a cool, dry place in order to maintain the integrity of the gel. The product should always be kept at a temperature between 2° C to 25° C.

Expiry (shelf life)

  • This gel has a shelf life of approximately 18 months from the date of manufacture.
  • Always check the expiration date on the packaging before use. Do not use this product after its expiry date. The ingredients of this product may lose their potency after the expiry date.